The purpose of this study is to investigate the long-term safety and any side effects of baricitinib in participants who have completed a previous baricitinib rheumatoid arthritis study. The study provides 7 years of additional treatment with baricitinib.

Elegibilidad

Edad mínima: 18 YearsSexo: ALL

Criterios de inclusión

Have completed the final active treatment in study JADV (NCT01710358), JADZ (NCT01711359), JADX (NCT01721057), JADW (NCT01721044), JADA (NCT01185353) or JAGS (NCT02265705)

Criterios de exclusión

Have significant uncontrolled cerebro-cardiovascular (eg, myocardial infarction \[MI\], unstable angina, unstable arterial hypertension, severe heart failure, or cerebrovascular accident), respiratory, hepatic, renal, gastrointestinal, endocrine, hematologic, neuropsychiatric disorders, or abnormal laboratory values that developed during a previous baricitinib study that, in the opinion of the investigator, pose an unacceptable risk to the participant if investigational product continues to be administered
Have a known hypersensitivity to baricitinib or any component of this investigational product
Had investigational product permanently discontinued at any time during a previous baricitinib study
Had temporary investigational product interruption at the final study visit of a previous baricitinib study and, in the opinion of the investigator, this poses an unacceptable risk for participation in the study
Have any other condition that, in the opinion of the investigator, renders the participant unable to understand the nature, scope, and possible consequences of the study or precludes the participant from following and completing the protocol

Ubicaciones

Hospital Italiano Regional del Sur

Bahía Blanca, Buenos Aires, Argentina

Atencion Integral en Reumatología

Ciudad Autonoma de Buenos Aire, Buenos Aires, Argentina

Instituto de Investigaciones Clínicas Mar del Plata

Mar del Plata, Buenos Aires, Argentina

Centro de Investigaciones Medicas Mar del Plata

Mar del Plata, Buenos Aires, Argentina

CER Instituto Medico

Quilmes, Buenos Aires, Argentina

Instituto de Investigaciones Clinicas Quilmes

Quilmes, Buenos Aires, Argentina

Instituto Medico de Alta Complejidad San Isidro

San Isidro, Buenos Aires, Argentina

CENIT Centro de Neurociencias, Investigación y Tratamiento

CABA, Ciudad Autonoma Buenos Aires, Argentina

Instituto Centenario

CABA, Ciudad Autonoma de Buenos Aire, Argentina

Centro de Enfermedades del Higado y Aparato Digestivo

Rosario, Santa Fe Province, Argentina

Instituto CAICI SRL

Rosario, Santa Fe Province, Argentina

Centro Medico Privado de Reumatologia

SAN M. de Tucuman, Tucumán Province, Argentina

CIR Centro de Investigacions Reumatologicas

San Miguel de Tucumán, Tucumán Province, Argentina