A Randomized, Double-Blinded, Placebo-Controlled, Study to Evaluate the Safety and Tolerability of BMS-986259 in Stabilized Patients Hospitalized for Acute Decompensated Heart Failure

CompletadoFase 2ClinicalTrials.gov

ID: NCT04318093Tipo: INTERVENTIONALInicio: 6 de nov de 2020Fin estimado: 19 de jul de 2021

Traducción no disponible, mostrando original

Resumen

The purpose of the study is to assess the safety of BMS-986259 in stable participants hospitalized for acute decompensated heart failure.

Elegibilidad

Edad mínima: 18 YearsSexo: ALL

Criterios de inclusión

For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com
Participants currently hospitalized for acute decompensated heart failure (ADHF)
Participants must be hemodynamically stable, as assessed by the investigator
Men must agree to follow specific methods of contraception, if applicable, while participating in the trial
Women participants must have documented proof that they are not of childbearing potential

Criterios de exclusión

Acute cardiovascular condition other than heart failure (HF) decompensation
Cardiogenic shock at presentation to emergency room (ER) or at any time before randomization
Recipient of ventricular assist devices or use of any cardiac extracorporeal devices, within 12 weeks of study randomization
Participants with contraindications to vasodilator therapy such as restrictive or obstructive cardiomyopathy, severe mitral or aortic stenosis

Intervenciones

drug

BMS-986259

Specified dose on specified days

other

Placebo

Specified dose on specified days

Ubicaciones

Local Institution - 0009

Ciudad de Buenos Aires, Buenos Aires, Argentina

Local Institution - 0007

Alberdi, Córdoba Province, Argentina

Local Institution - 0028

Córdoba, Córdoba Province, Argentina

Local Institution - 0010

Córdoba, Córdoba Province, Argentina

Local Institution

Buenos Aires, Distrito Federal, Argentina

Local Institution - 0025

Córdoba, Argentina

Patrocinadores

PrincipalBristol-Myers Squibb

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