Prospoctive cohort of high-dose cyclophosphamide exposed patients. With active estandardize screening of hyponatremia development in the follow up period.
Primary objectives 1. To identify the factors associated with the development of hyponatremia in patients receiving high-dose cyclophosphamide (2.5 grams or more). 2. Generate and validate a predictive score of developing hyponatremia high-dose cyclophosphamide. 3. To estimate the incidence of hyponatremia in patients undergoing high-dose cyclophosphamide. Study design. Observational prospective cohort study of Patients after infusion of high-dose cyclophosphamide. Follow up period will be from cyclophosphamide infusion until one month after hospital discharge.
Buenos Aires, Buenos Aires F.D., Argentina
Diego H Giunta, MD · diego.giunta@hospitalitaliano.org.ar · +54 9 11 5825-6489