The purpose of this study is to evaluate the efficacy and safety of JNJ-78934804 as compared to guselkumab and golimumab in participants with moderately to severely active ulcerative colitis who have had an inadequate initial response, loss of response, or intolerance to one or more approved advanced therapy.
Guselkumab will be administered as subcutaneous injection.
Golimumab will be administered as subcutaneous injection.
JNJ-78934804 will be administered subcutaneously as per defined regimen.
Placebo will be administered as subcutaneous injection.
Buenos Aires, Argentina
Buenos Aires, Argentina
Ciudad Autonoma Buenos Aires, Argentina
Córdoba, Argentina
Mar del Plata, Argentina
Rosario, Argentina