To demonstrate that Micardis and Norvasc when used together are more effective at lowering blood pre ssure.

Elegibilidad

Edad mínima: 18 YearsSexo: ALL

Criterios de exclusión

Patient is pregnant; breast-feeding; unwilling to use birth control during the study; has secondary hypertension; severe renal dysfunction; hepatic insufficiency; stroke within the last six months; myocardial infarction, cardiac surgery, percutaneous transluminal coronary angioplasty, unstable angina or coronary artery bypass graft within the past three months; unstable or uncontrolled diabetes for the past three months defined as a glucosylates hemoglobin (HbA1c) greater than ten percent ; history of angioedema or hypersensitivity related to either study drug.
Systolic Blood Pressure (SBP) is greater than or equal to 180 millimeters of mercury (mmHg), Diastolic Blood Pressure (DBP) is greater than or equal to 110 mmHg.

Intervenciones

drug

Telmisartan 40 mg

Telmisartan 40 mg once daily for eight weeks

drug

Amlodipine 10 mg

Amlodipine 10 mg once daily for six weeks

drug

Telmisartan 20 mg

Telmisartan 20 mg once daily for eight weeks

drug

Telmisartan 80 mg

Telmisartan 80 mg once daily for eight weeks

drug

Amlodipine 10 mg

Amlodipine 10 mg once daily for six weeks

drug

Telmisartan 20 mg

Telmisartan 20 mg once daily for eight weeks

drug

Amlodipine 5 mg

Amlodipine 5 mg once daily for two weeks

drug

Amlodipine 5 mg

amlodipine 5g once daily for eight weeks

drug

Telmisartan 20 mg

Telmisartan 20 mg once daily for eight weeks

drug

Amlodipine 5 mg

Amlodipine 5 mg once daily for eight weeks

drug

Amlodipine 5 mg

amlodipine 5mg once daily for eight weeks

drug

Amlodipine 5 mg

Amlodipine 5 mg once daily for two weeks

drug

Placebo

Placebo to Telmisartan and Amlodipine once daily for eight weeks

drug

Telmisartan 20 mg

Telmisartan 20 mg once daily for eight weeks

drug

Amlodipine 2.5 mg

Amlodipine 2.5 mg once daily for eight weeks

drug

Amlodipine 2.5 mg

Amlodipine 2.5 mg once daily for eight weeks

drug

Amlodipine 10 mg

Amlodipine 10 mg once daily for six weeks

drug

Amlodipine 2.5 mg

Amlodipine 2.5 mg once daily for eight weeks

drug

Telmisartan 80 mg

Telmisartan 80 mg once daily for eight weeks

drug

Telmisartan 80 mg

Telmisartan 80 mg once daily for eight weeks

drug

Amlodipine 5 mg

Amlodipine 5 mg once daily for two weeks

drug

Amlodipine 2.5 mg

Amlodipine 2.5 mg once daily for eight weeks

drug

Telmisartan 40 mg

Telmisartan 40 mg once daily for eight weeks

drug

Telmisartan 40 mg

Telmisartan 40 mg once daily for eight weeks

drug

Amlodipine 5 mg

amlodipine 5g once daily for two weeks

drug

Amlodipine 5 mg

Amlodipine 5 mg once daily for eight weeks

drug

Telmisartan 40 mg

Telmisartan 40 mg once daily for eight weeks

drug

Telmisartan 80 mg

Telmisartan 80 mg once daily for eight weeks

drug

Amlodipine 10 mg

Amlodipine 10 mg once daily for six weeks

Ubicaciones

1235.1.001 Boehringer Ingelheim Investigational Site

BsAs, Argentina

1235.1.004 Boehringer Ingelheim Investigational Site

Buenos Aires, Argentina

1235.1.005 Boehringer Ingelheim Investigational Site

Buenos Aires, Argentina

1235.1.006 Boehringer Ingelheim Investigational Site

Buenos Aires, Argentina

1235.1.002 Boehringer Ingelheim Investigational Site

Carlos Paz, Argentina

1235.1.003 Boehringer Ingelheim Investigational Site

Córdoba, Argentina

A Randomized, Double-blind, Double-dummy, Placebo-controlled, 4x4 Factorial Design Trial to Evaluate Telmisartan 20, 40 and 80 mg Tablets in Combination With Amlodipine 2.5, 5 and 10 mg Capsules After Eight Weeks of Treatment in Patients With Stage I or II Hypertension, With an ABPM Sub-study

Resumen

Elegibilidad

Criterios de exclusión

Intervenciones

Telmisartan 40 mg

Amlodipine 10 mg

Telmisartan 20 mg

Telmisartan 80 mg

Amlodipine 10 mg

Telmisartan 20 mg

Amlodipine 5 mg

Amlodipine 5 mg

Telmisartan 20 mg

Amlodipine 5 mg

Amlodipine 5 mg

Amlodipine 5 mg

Placebo

Telmisartan 20 mg

Amlodipine 2.5 mg

Amlodipine 2.5 mg

Amlodipine 10 mg

Amlodipine 2.5 mg

Telmisartan 80 mg

Telmisartan 80 mg

Amlodipine 5 mg

Amlodipine 2.5 mg

Telmisartan 40 mg

Telmisartan 40 mg

Amlodipine 5 mg

Amlodipine 5 mg

Telmisartan 40 mg

Telmisartan 80 mg

Amlodipine 10 mg

Ubicaciones

1235.1.001 Boehringer Ingelheim Investigational Site

1235.1.004 Boehringer Ingelheim Investigational Site

1235.1.005 Boehringer Ingelheim Investigational Site

1235.1.006 Boehringer Ingelheim Investigational Site

1235.1.002 Boehringer Ingelheim Investigational Site

1235.1.003 Boehringer Ingelheim Investigational Site

Patrocinadores